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Description
In some cases, the allostatic load 28 can exceed what the neuroendocrine response (aka the HPA axis response) is capable of managing, which is referred to as allostatic overload

DOI: 10.1016/s0928-4257(99)00120-5 10.1016/s0928-4257(99)00120-5 Sikiric.P, Seiwerth.S, Rucman.R, Turkovic.B, Rokotov.D, Brcic.L, Sever.M, Toxicity by NSAIDs

Desale K, Kuche K, Jain S

Actions in the HPA axis kick-start the bodys natural stress reaction system, commonly referred to as the NeuroEndoMetabolic (NEM) stress response
