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IGF-1 and its receptor IGF-1R are involved in these critical pathways and therefore play a pivotal role in healthy tissue homeostasis but also a far less desirable role in diseases such as cancer where they can be responsible for the survival and proliferation of malignant cells

Regulation of insulin secretion: role of mitochondrial signalling

The A peptide of Alzheimers disease directly produces hydrogen peroxide through metal ion reduction

Exposure of rats to TQ blocked sodium nitrite-induced elevation in TNF- and pro-inflammatory cytokines in brain tissue and reduction of IL-10, but it did not affect the control rats (Fig