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The authors of that study concluded that neurogenic mechanisms contributed to asthma

Despite these advancements, the comprehension of the specific molecular mechanisms underlying cardiovascular cell senescence remains limited, for example, how the ageing of a single cardiac cell type leads to a specific disease phenotype and how to screen highly selective markers for ageing cardiovascular cells ( Investigational treatments are currently being explored with the goal of achieving overall suppression of senescence and/or clearance of senescent cells

From these data it has been possible to glean some understanding of mechanisms of primary injury and the long-term consequences and health significance