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These effects are achieved through an increase in tumor-suppressor protein p53 levels and a reduction in kallikrein-related peptidase (KLK1, 2, 4, 9, and 10) gene expression

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In metabolomics, metabolite set enrichment analysis is used to identify the altered metabolite sets (metabolic pathways) associated with phenotypes of interest, e.g., presence of fatigue, using algorithms which is run on a general metabolite network constructed based on public databases, i.e., KEGG (Kyoto Encyclopedia of Genes and Genomes) in the present study 57,58,59

nucleic acid sequence refers to RNA, DNA, cDNA or any synthetic variant thereof which encodes for protein