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Description
J Hypertens 33: 11281136, 2015
Rare mutations that cause a deficiency of CNNM2 result in too much magnesium being excreted in the kidneys, which is linked to a loss of circadian rhythm in blood pressure control.[ref] Rare mutations in CNNM2 are also linked to brain development disorders due to the dysregulation of magnesium.[ref] Magnesium and calcium levels interact through several regulatory mechanisms
But it means your kidneys are working at roughly 50% capacity, and injecting additional compounds that require renal clearance is a risk you should know about before you start
doi: 10.1186/1471-2202-11-51 114
