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Methylcobalamin B12 has also been shown to be superior in tackling sleep disorders, since it is believed to influence melatonin synthesis

The idea here is that, as a fragment of hGH, it might retain some of the hormone's regenerative signaling properties without the systemic side effects

However, with direct injection, if you do not need the additional B12, it may result in high levels in your blood that can cause side effects including gastrointestinal issues, headache and dizziness, tiredness and weakness, or skin irritation until the excess is flushed out via your kidneys and urine

Excessive activation of the RES, as seen with certain immune-mediated, infectious, inflammatory and paraneoplastic conditions, can also stimulate early removal of RBCs from the circulation