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Synthetic peptides activating discoidin domain receptor 2 and collagen-binding integrins cooperate to stimulate osteoblast differentiation of skeletal progenitor cells

Its use is limited to one year due to its association with increased incidence of cardiovascular and cerebrovascular events (eg, heart attack and stroke), as well as atypical femur fractures and osteonecrosis of the jaw

Bring any B12 lab work if available your NP will advise on frequency

However, if extremely high doses are given for a long time, pyridoxine can cause nerve damage leading to numbness or tingling in the hands and feet (peripheral neuropathy)