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GSH content doubled in HCC biopsies as compared to normal liver, due to increase in GCL heavy subunit and GS

Polyol pathway hyperactivity is closely related to carnitine deficiency in the pathogenesis of diabetic neuropathy of streptozotocin-diabetic rats J Pharmacol Exp Ther 1998

The antimetabolite nature of MTX and its inhibitory effect on many important metabolic enzymes prompted us to study the consequences of MTX treatment on cellular metabolism
