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Liver sinusoidal endothelial cells constitutively express all molecules necessary for antigen presentation (CD54, CD80, CD86, major histocompatibility complex [MHC] classes I and II, and CD40) and can function as antigen-presenting cells for CD4 + and CD8 + T cells.40, 41 Thus, these cells probably contribute to hepatic immune surveillance by activation of effector T cells

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