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All these drugs are present a demonstrated senolytic acitivity in vitro and in vivo (Fig.1) but their efficiency in human still need to be investigated
Then, the cells were rinsed three times with PBS before the DHE fluorescence probe was loaded for 20 min at 37 C

How it works (mechanism of action) Not fully understood, but is seems to act like a cellular repair crew

Further network analyses of the SEPT9-interactome data clearly revealed a cluster of proteins with markedly reduced interactions as the septin complex (Fig
