Immunogenicity in Antibody Therapeutics
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Description
The alkaline environment of the cytoplasm leads to histone acetylation, gene expression and increased protein synthesis, whereas the acidic conditions in the TME contribute to maximal P-gp catalytic activity (Assaraf et al., 2019)
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10.1038/ki.2014.244 50 RubinowK
Boerke, A
