b12 supplements vs injections What Are the Benefits of Vitamin Injections? vitamin b12 supplements vs injections

The Pernicious Anaemia Society notes this is well recognised but not fully understood

Evaluation of: Glycerol production (a marker of lipolysis) 2-deoxyglucose uptake (a marker of insulin signaling) DNA synthesis (a marker of proliferation) What they found: AOD-9604 stimulated lipolysis dose-dependently from 10 M, with a plateau at 10 M Full hGH stimulated lipolysis to a similar maximum, but with different kinetics AOD-9604 did not affect glucose uptake or DNA synthesis at all, whereas hGH inhibited both (the classic lipotoxic GH effect) Fragments with different sequence (from the N-terminal part of hGH) had no lipolytic effect Why it matters: This was the first publication of AOD-9604

References Heffernan MA et al

Guideline 4: Measurement and Concentration Standards Getting the right amount of vitamin B12 in injections is very important