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DC activation and maturation is a highly coordinated response associated with phenotypic and morphologic changes, which enable functional specialization for mounting protective immunity or tolerance to self-antigens 2

They likely reflect the difference between pathological IGF-1 excess (which does appear to increase cancer risk and accelerate ageing in some models) and normalisation of IGF-1 in individuals whose levels have declined below an optimal physiological range due to somatopause

Genesis Lifestyle Medicine providers often recommend tailored nutrition and fitness plans to ensure you get the most from your treatment program

Artif Organs (2019) 43:47889