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Cystine Transporter SLC7A11/xCT in Cancer: Ferroptosis, Nutrient Dependency, and Cancer Therapy

Results Docking and MD simulation study reveals high affinity to NLRP3 PYD The docking study of 4-MESC and NLRP3 PYD was performed to check the affinity

Irwin RE, Cook D, Richardson LL, Manson JS, Gardner DR

De Leo E, Elmonem MA, Berlingerio SP, Berquez M, Festa BP, Raso R, Bellomo F, Starborg T, Janssen MJ, Abbaszadeh Z, Cairoli S, Goffredo BM, Masereeuw R, Devuyst O, Lowe M, Levtchenko E, Luciani A, Emma F, Rega LR (2020) Cell-based phenotypic drug screening identifies luteolin as candidate therapeutic for nephropathic cystinosis
