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However, its compelling basic highlights (particular vascular effect, activation of the collateral pathways) [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41] in the most valuable animal models might still be far from the vast clinical evidence obtained in the huge number of clinical trials [1]

[DOI] [PubMed] [Google Scholar] 89.Chhabra A., Bashirians G., Petropoulos C.J., Wrin T., Paliwal Y., Henstock P.V., Somanathan S., da Fonseca Pereira C., Winburn I., Rasko J.E.J

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It may well be true that the IGF-1 levels obtained during long-term GH administration are too high to preserve or improve memory functions, and may even result in memory impairment