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Wolf, N

The expansion and balance between pro-inflammatory CD4 + T eff cells and anti-inflammatory CD4 + T reg cells determine the pathogenic development of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS), which is an inflammatory demyelinating disease of the central nervous system (CNS)

Next, we assessed the cross-reactivity of SCG101 with human peptides and potential off-target activity

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