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A 7kg terrier and a 40kg Labrador have very different nutritional needs, and giving the same amount to both would leave one under-supported and the other over-supplemented

Although there is evidence that prepro-TRH 178-199 can inhibit both basal and CRH-stimulated ACTH release in AtT-20 cell lines and rat anterior pituitary cells (136,137), other investigators have not been able to confirm this (138)

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