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Targeting 5-HT(1A) receptors in astrocytes to protect dopaminergic neurons in parkinsonian models
Upregulation of CHAC1 has been consistently observed in models of retinal damage, kidney and liver injury and heat shockinduced oxidative stress, often in tandem with ER stress ( In acetaminophen (APAP)-induced liver injury, CHAC1 indirectly promotes ferroptosis by modulating the ferroptosis suppressor ARF6
doi: 10.1016/bs.afnr.2022.08.002
[DOI] [PubMed] [Google Scholar] 172.Ray P.D., Yosim A., Fry R.C
