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Hypervascularization is an epiphenomenon of the ionizing radiation damage in melasma while participating in the maintenance of hyperpigmentation

J Clin Endocrinol Metab 1971;33:33242

Bolton WD, Rice DC, Goodyear A, Correa AM, Erasmus JJ, Hofstetter WL, Komaki R, Mehran RJ, Pisters K, Roth JA, Swisher SG , Vaporciyan AA, Walsh GL, Weaver J, Rhines L

The main pathological manifestation of PD is the huge loss of dopaminergic neurons owing to the accumulation of reactive oxygen species (ROS) and the abnormal aggregation of the -synuclein (-syn) protein
