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The delay in 53BP1 recruitment to DSBs in these cells and the accumulation of irreparable damage may be a potent physiological genotoxic stress in individuals with HGPS
Copper peptides are naturally produced by our bodies, but as we age, the amount that we have is significantly reduced
The product of this reaction, phosphatidyl ethanol, is poorly metabolized and may accumulate to detectable levels following chronic consumption of large amounts of alcohol, but its effects on the cell remain to be established
Journal of cachexia, sarcopenia and muscle, 1(1), 23-33
