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Description
Once dissolved in laboratory buffer, aliquot and store at -20C
Potential mechanisms range from changes in the extracellular matrix (myocardial fibrosis, inflammation) 79 to impaired calcium handling 80 or modification of sarcomeric proteins, 81 which have all been reviewed by others
Miranda advocates that in cases where the skin surrounding the nail is involved, this skin should also be biopsied, even if it is less pigmented than the primary lesion
doi: 10.1038/oby.2009.510
