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Given the similarities in mucus barriers across different organs, inhalable drug delivery may explore and try to apply strategies used in the gastrointestinal and vaginal mucus to enhance diffusion and retention in the airway 284,285,286,287,288

1 Introduction The incidence of fungal infections has significantly increased in recent years, ranging from mild allergic reactions to potentially life-threatening invasive fungal diseases (IFDs) (Kronstad et al., 2011

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This enrichment is crucial for maximizing the likelihood of detecting therapeutic effects and for avoiding the inclusion of patients unlikely to benefit from the intervention