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Loftspring MC, Johnson HL, Johnson AJ, Clark JF
Cells lacking PINK1 exhibit a stronger response to iron overload, and the mRNA levels of the iron storage proteins FTH1 and FTL1 are significantly increased, indicating that the iron metabolic response is altered (197)
A recent study suggests that miR-20a-5p has potential therapeutic applications in kidney transplantation by inhibiting ACSL4-dependent ferroptosis [374]
These methods combined allow for the simultaneous identification and imaging of various free radicals, providing metabolic and biochemical data revealing significant differences between whole-cell and mitochondrial metabolite profiles (Domingo-Ort et al., 2023
