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Further functionalization with diverse substituents at various positions endows quinoline-based fluorescent probes with unique photophysical characteristics ( 2-((2-(Hydroxymethyl)quinolin-8-yl)oxy)-N-(quinolin-8-yl)acetamide (Probe) is a quinoline-based fluorescent probe, exhibits good water solubility

This leads to mitochondrial oxidative and nitrosative stress, accompanied by activation of c-jun N -terminal kinase (JNK) and its translocation to the mitochondria

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After the therapy had concluded, therapeutic effects were sustained for two to four months suggesting that in untreated PD, glutathione has symptomatic efficacy