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RNA and protein extraction After the addition of glass beads (0.751.00 mm diameter, Carl Roth, Karlsruhe, Germany), lyophilized trichomes (~ 10 mg dry mass) or leaf material (two leaves) were frozen in liquid nitrogen and ground three times for 1 min at 30 s 1 using a bead mill (Retsch, Haan, Germany)

Accordingly, in certain aspects, provided herein are methods for preventing or treating cancer using the CpG-containing immunostimulating polynucleotide in combination with at least one additional cancer therapeutic agent

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