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To view a copy of this license, visit About this article Cite this article Warfel, J., Bermudez, E., Mendoza, T

Human skin penetration of hyaluronic acid of different molecular weights as probed by Raman spectroscopy, 14

Before use, the lyophilized DSIP peptide must be reconstituted using high purity Bacteriostatic Water

Sequence 3: Sandwich method (for sensitive skin) Cleanse Light layer of moisturizer Apply retinol Apply peptide serum Final layer of moisturizer Best for: Reducing retinol irritation while still getting benefits Wait time between layers 1-2 minutes between products is ideal: Allows first product to absorb Prevents pilling or mixing on skin surface Maximizes penetration of each ingredient Don't wait too long: 5+ minutes unnecessary Skin dries out between applications Makes subsequent products harder to spread Morning vs evening application Evening routine (most common approach): Evening: Peptide serum + Retinol + Moisturizer Why: Retinol degrades with sun exposure