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Its anti-inflammatory effects are mediated by its ability to suppress the expression and release of pro-inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-), in various cell culture models

Animal studies showed that BPC-157 has great potential for rats suffering inflammation and toxic or surgical trauma, such as healing tendons, nerves, joints, skin, stomach and intestinal tract

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It is particularly common among older demographics, where skin becomes less effective at producing Vitamin D, or among people with darker complexions