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CSE is a highly inducible protein and can be regulated by several factors depending on the cell type and tissue (Figure 2C)

Despite numerous challenges, the synergistic role of ferroptosis and immune cell death (ICD) has opened up new dimensions for tumor treatment, and its successful translation will depend on the close integration of in-depth exploration of mechanisms and technological innovation

Impaired inflammasome activation and bacterial clearance in G6PD deficiency due to defective NOX/p38 MAPK/AP-1 redox signaling

Functional consequences of the disruption of -globin-eNOS binding via an -globin mimetic peptide have been observed ex vivo, by increased NO sensitivity of isolated small arteries from mice and humans (124, 166), and in vivo, in lowering of systemic blood pressure in mice (164)