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Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-B

We have shown that TPC-1 cell line did not respond to the RSL3 treatment when compared to BRAF or RAS mutant PTC cell lines, thus confirming that the effects observed in other PTC cell lines is in fact a GPX4-specific process
For instance, Yates et al
