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Identification of ACSL4 as a biomarker and contributor of ferroptosis

6.3.3 Trial-design lessons Future trials should: enrich for participants with high redox/ferroptosis burden (biomarker-enriched enrollment)

Additionally, a single nucleotide polymorphism (SNP) found in the blood samples further suggested that imprinting abnormalities may be linked to the risk of developing AD, supporting the hypothesis that early-life environmental exposures could increase the risk of AD in later life (48)

Owing to these capabilities, such probiotics are increasingly being explored as adjuncts in immunotherapeutic strategies for specific disease states, including certain forms of cancer (219)