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Recent studies have shown that administration of moderate doses of EGCG to mice can produce ROS, which activates the Nrf-2-mediated induction of antioxidant and other cytoprotective enzymes [14, 15]
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Component C5a of the complement system, recognized for its potent pro-inflammatory effects, can amplify monocyte and neutrophil activation
Serra G, Giuffr M, Piro E, Corsello G