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Regarding to immune response, oxaliplatin-treated neurons release significant amounts of pro-inflammatory cytokines, mainly TNF- and IL-6, whereas prostaglandin E2 levels were significantly higher in macrophagues exposed to the platinum compound than in control cells

Park SU, Walsh L, Berkowitz KM

Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

doi: 10.2478/jomb-2018-0046
