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Microsc Res Tech 86:13781390 He Y, Xi J, Fang J, Zhang B, Cai W (2023) Aloe-emodin alleviates doxorubicin-induced cardiotoxicity via inhibition of ferroptosis

As regards the pathogenic mechanisms, the occurrence of an oxidant stress (resulting from an impaired homocysteine metabolism, which modifies the redox status of extra- and intracellular thiols and thus alters the intracellular redox potential) might play a central role in moderate hyperhomocysteinemia-mediated vascular disorders

GSTP1 is also involved in the detoxification process of benzo(a)pyrene (BaP), which excretes the conjugates of BaP metabolism and detoxification (52)

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