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Although keeping sulfide concentrations in the narrow therapeutic range appears to be critical, currently available pharmacological tools (e.g., inhibitors of H 2 S-producing enzymes) fail to achieve this goal

Additional studies have demonstrated that ganoderic acid A (GAA) and artemisinin may mitigate neuronal damage by modulating iron metabolism and the antioxidant system

Shahid M, Kim J, Leaver K, et al
AJR Am J Roentgenol 187(2):351357 Shichita T, Ago T, Kamouchi M, Kitazono T, Yoshimura A, Ooboshi H (2012) Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke
