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Interestingly, expression of Igf1r was found upregulated in Treg cells and IGF1R-deficient Treg cells were reported to express lower levels of FOXP3 [70, 71]
doi: 10.1016/j.canlet.2013.03.030
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Compared with the MPTP-treated group, irisin restored the activity of superoxide dismutase (SOD), which had been impaired by MPTP (Fig
