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Consistent with these data, nitric oxide increases oxidative stress, and several studies show that nitric oxide inhibitors decrease inattention and hyperactivity in rat models of ADHD (e.g., Aspide, Gironi Carnevale, Sergeant, & Sadile, 1998

This regulatory mechanism underscores DJ-1s crucial role in cellular defense against oxidative stress, highlighting its potential as a therapeutic target for neurodegenerative diseases and conditions involving oxidative damage (Wang H

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Oncogene (2007) 26(56):77418
