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Importantly, these epigenetic alterations have been shown to persist beyond the period of active androgen exposure, even after partial normalisation of circulating hormone levels
(Gaggin 2021) However, first-degree AV block may also be associated with a risk of atrial fibrillation and more severe conduction abnormalities
Among them, LRRK2 is one of the most associated with PD
The rarefaction curves for all samples exhibited clear asymptotes, indicating a near-complete sampling of the community (Supplementary Figure 4)
