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In vivo fluorescence studies in the tumor microenvironment (TME) revealed a fluorescent signal in the intracellular environment in the spheroids confirming the activation of apoptotic machinery which releases caspase 3 enzymes and activates the fluorescent dye

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* Data not separated by race/ethnicity # Subsequent visits by the same patient were included in the data pool PIH = Postinflammatory hyperpigmentation FST = Fitzpatrick skin types Etiology Many types of inflammatory dermatoses or cutaneous injuries can cause pigmentary changes