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The following Medical Subject Heading and free-text search terms associated with vitamin B 12 were input: vitamin B12 OR cobalamin OR cyanocobalamin OR methylcobalamin OR adenosylcobalamin OR hydroxycobalamin OR holotranscobalamin OR B12 deficiency OR vitamin B12 metabolism, which were first used singly and then subsequently matched, in turn, with the terms associated with COVID-19 and other respiratory viral infections: COVID OR COVID-19 OR SARS-CoV-2 OR SARS-CoV OR MERS OR respiratory infection OR viral infection OR viral disease. 34 The third round of searches ensued with terms referring to how the virus gains entry and causes damage in organs

NADPH or ATP concentrations were evaluated using a calibration curve and normalized to the protein level

Its natural presence in the body contributes to its perceived safety profile

doi: 10.1073/pnas.0904489106