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This work has received support from Utragenyx for medical writing and figure creation
there is abundant melanin accumulation within the basal cell region with melanin incontinence
This ensures that comparisons across time are aligned and actionable
The AT mechanism of all of the above-mentioned compounds usually involves conversion of manganese to an Mn IV -oxo form, which is then reducible by endogenous or exogenous AT (e.g., glutathione or vitamin C) activity (Halliwell and Gutteridge, 2015)
