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Description
In the pathogenesis of RA, CD4 T cells account for a large proportion of the inflammatory cells that invade synovial tissue
R.GongL.CaudleK
The subunit contains two domains, one of which binds to the coenzyme thiamine pyrophosphate (TPP), which is essential for the catalytic activity of PDH
However, mice have several key lung morphological and physiological differences compared to humans such as breathing pattern (mice are primarily nose-breathers), cell composition (mice largely lack submucosal glands except in the trachea), and eosinophil function and distribution [102]
