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Indeed, lower serum concentrations of IFN in patients with COVID-19 have been linked to an increased risk of developing pulmonary fibrosis 47

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A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

However, no difference in the p53 expression levels was observed in the presence of the proteasome inhibitor MG132, suggesting that proteasomal degradation of p53 is suppressed in MKRN1 knockout (KO) HT1080 cells (Extended Data Fig
