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[PubMed: 15472192] 878

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Apart from low folate absorption levels related to riboflavin-deficiency-induced gut inflammation (49), riboflavin is required for biosynthesis of folate coenzymes without which lower levels of useful folate are found in animal studies (50)

SB-01 is a synthetic 7-amino-acid peptide in clinical trials that downregulates TGF-beta-1, a growth factor highly expressed in degenerated discs