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Deficiencies in Vitamin B12 have many side effects but mainly consist of elevated rates of DNA damage with links to general weakness, loss of balance, depression, and anemia
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
48 , 113 Cyanocobalamin must be broken down to cobalamin and cyanide must be converted to the active forms of B 12 in the human body, whereas genetic single nucleotide polymorphisms can interfere in the metabolism and conversion to intracellular active forms of vitamin B 12
