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55 WuY.XiaY.HuA.XiongG.WuW.ShiL.et al

Monomeric fractions of hFcRn-His were isolated by SEC using a Superdex 200 Increase 10/300 column (Cytiva Life Sciences) with an KTA Avant 25 (Cytiva Life Sciences)

However, it increased heart rate, cardiac output, and induced myocardial degeneration in mice and thus was terminated as a preclinical candidate (Yau et al., 2017)