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Experimental studies showed that the combination of a drug and Pgp modifier can produce MDR mediated by topoisomerase II alterations

J Endocrinol 142:453462 Yakar S, Setser J, Zhao H, Stannard B, Haluzik M, Glatt V, Bouxsein ML, Kopchick JJ, LeRoith D (2004) Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1-deficient mice

Structural characterization and identification of major constituents in radix scrophulariae by HPLC coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry

In Figure 3C, the group treated with PECF was found to decrease lactase activity by 60% and 57.5% in the two largest concentrations when compared to the control group