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Some families of Boxers have been diagnosed with primary carnitine deficiency, while Cocker Spaniels with inherited DCM have also responded well to carnitine supplementation

Antioxidant effect of L-carnitine and its short chain esters: relevance for the protection from oxidative stress related cardiovascular damage

Isopropyl Alcohol, Propylene Glycol, Aqua (Water), Benzyl Alcohol, Triglyceride Complex, N-Methyl-2-Pyrrolidone, L-Carnitine, Propionyl L-Carnitine, Menthol, Carbomer

Western blotting Protein samples were separated by electrophoresis and transferred to a nitrocellulose membrane (Millipore, USA), blocked with 5% non-fat milk for 2 h, and then incubated overnight at 4 C with primary antibodies specific for PCNA (WANLEIBIO), cyclin A (WANLEIBIO), CDK2 (Bioss), TGF- (Bioss), Caspase 3 (Bioss), Bax (Boster), Bcl-2 (Bioss), MMP2 (Bioss), MMP9 (Bioss), AMPK1 (Bioss), HSP47 (Boster), NLRP3 (WANLEIBIO), Caspase 1 (WANLEIBIO), IL-18 (Affinty), and IL-1 (Bioss)