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GS-ylated hemoglobin increases in several human diseases and it could be used as a clinical biomarker of oxidative stress (see paragraph on Kidney Diseases and [132])

Cost note: At 2-5 mg/kg for a 75 kg individual (150-375 mg per injection), FOXO4-DRI becomes one of the most expensive peptide protocols due to both the high dose and D-amino acid synthesis costs

Aritra Mukherjee : Structured the chapter, synthesized interdisciplinary perspectives, and coordinated editing, and writingoriginal draft

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