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Plants lacking both these transporters are unable to take up sulfate in low concentrations and are strongly affected in growth (Yoshimoto et al., 2002, 2007

Nov 1;33(21):348991
Evidence obtained both through clinical studies and pre-clinical research with the EAE model suggest adaptive peripheral immune activity is exerted mainly through CD4+ Th-1 and Th-17 lymphocytes, in a B-cell antigen-presentation dependent manner

Their importance in brain osmoregulation and tissue swelling has been demonstrated in global AQP4 knockout mouse models
