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ANOVA Institute for Regenerative Medicine (IRM) utilizes Stem Cell Secretome, a cutting-edge, cell-free therapeutic derived from the paracrine factors of Mesenchymal Stem Cells (MSCs)

A reasonable starting framework, based on extrapolation from GLP-1 nasal delivery literature, might look like this: Conservative approach: Begin with 0.5-1mg per nasal actuation, administered once daily

Unlike M1 macrophages, which stimulate T cell response thereby inducing an increase in IFN production in anti-CD3-activated PBMC/M1 co-culture, M2 macrophages exhibit a suppressive activity of T cell activity shown through IFN level decrease